1. Smoking: The animal experiment shows that the animals feeding on tobacco water may develop pancreatic cancer. Apart from that, the result of a survey indicates that the chance of developing pancreatic cancer for smokers is 1.5 times higher than the nonsmokers. The incidence of pancreatic cancer is parallel to the amount of cigarettes.

2. diet: Some scholars attribute the high incidence of pancreatic cancer to unreasonable dietary structure. The experiment proves that the animal feed on diet high in fat and protein are more sensitive to carcinogenic

substances and accelerate the renewing of cells of pancreatic duct. Some scholars in China come up with a viewpoint that dietary structure has a close relationship with the onset of pancreatic

cancer and those who take too much meat are more inclined to develop the disease.3. Chronic pancreatitis: The research of epidemiology approves that most chronic pancreatitis can progressed to pancreatic cancer. The research of Fries shows that the expression of 34 genes in pancreatic cancer and chronic pancreatitis reduce and the expression of 152 genes in chronic pancreatitis strengthen among total 5600 genes. And the expression of 152 genes in pancreatic cancer also strengthens. That can prove that chronic pancreatitis has some relationship with pancreatic cancer.4.Diebetes: The experiment shows that insulin can promote the growth of cells of pancreatic cancer. High concentration of insulin can activate the receptor of insulinoid growth factor and change the mitotic cycle.5. Hp: The survey shows that the result of Hp serum is positive and has an obvious difference compared with the control group which indicates that infection of Hp has certain relationship with pancreatic cancer.6. Coffee: The survey finds that coffee can increase the chances of developing pancreatic cancer as high as 4 times. Besides, the research also proves that coffee can inhibit the replication of DNA and trigger the mitosis before the accomplishment of the replication which is a main cause of pancreatic cancer.

As we all know, pancreatic cancer is referred as “the king of cancer” for that it has high malignancy and may spread to other sites of the body in a short period of time. Therefore, it is relatively difficult for the doctors to deal with pancreatic cancer. Generally speaking, if someone is diagnosed with pancreatic cancer, surgery is usually recommended as the first choice to remove the tumor which can offer greater chances for survival. However, the actual condition is not as optimistic as imaged for that surgery is usually inappropriate in most cases. Then, the doctors would try their best to seek for other treatment methods.

Generally speaking, chemotherapy or radiotherapy will be applied in the treatment of pancreatic cancer. However, it can not obviously improve the patients’ condition. On one hand, simplex chemotherapy or radiotherapy can not effectively kill the cancer cells in the body. On the other hand, most patients can not tolerate the serious side effects of chemotherapy or radiotherapy. As a result, the traditional treatment still can prevent the further progression of pancreatic cancer. Therefore, it is absolutely important for the doctor to find a new treatment method which can effectively delay the course the disease.

In recent few years, cell-based immunotherapy emerged as the latest effective therapy for cancer. For the treatment of pancreatic cancer, it has significant advantages over these traditional methods. In the first place, it has wide indications for patients with pancreatic cancer which means that most patients are suitable for the cell-based immunotherapy. Secondly, it can effectively eliminate the cancer cells in the body without damaging the normal cells because of its high targeting. Thirdly, it doesn’t have any side effects. Furthermore, it can obviously improve the patients’ quality of life and prolong the patients’ survival time.  Apart from that, if it is combined with chemotherapy or radiotherapy, the therapeutic effect would be better for that it can strengthen the patients’ immunity so that they can better tolerate the side effects of chemotherapy.

According to a study published in the journal Gut, diet high in antioxidants may help lower the risk of developing pancreatic cancer, such as Vitamin E, Vitamin C and selenium. The findings pointed out that people with a diet containing a higher amount of foods loaded with antioxidants are less likely to develop pancreatic cancer for that antioxidents can protect cells from the damage of "free radicals." And free radicals are destructive fragments of oxygen, which are linked to development of cancer and other diseases. The new study pointed out that there is a relationship between these foods and pancreatic cancer risk. However, the researchers have not figured out its mechanism of action.

As we all know, vitamins C and E and selenium are good for our general health. And the new study indicated that they may help prevent the development of pancreatic cancer. However, more study is needed. If this association turns out to be causal, antioxidants may help prevent as many as one in 12 cases of pancreatic cancer. The American Cancer Society estimates that about 43,920 people will be diagnosed with pancreatic cancer in 2012 and 37, 390 people of them will die from the disease.

Researchers have analyzed the seven-day food diaries of more than 23,500 people ranging from 40 to 74 years old. Then, researchers compared diets among people diagnosed with pancreatic cancer to those of nearly 4,000 people without pancreatic cancer. People who ate more selenium were 50% less likely to develop pancreatic cancer compared to those who ate the least amounts of selenium-rich foods. As we all know, people still don't have a good mastery of the cause of pancreatic cancer. Smoking and diabetes are commonly considered as risk factors. In recent few years, obesity is also referred as another potential risk. As a whole, this study is preliminary and shows an association between foods and pancreatic cancer.

Nevertheless, other studies have shown that high amounts of vitamin E and selenium may increase risk of other cancers, such as prostate cancer. Therefore, people have different opinions in the medical field. There is no doubt that it may implicate some nutritional factors in causing pancreatic cancer. In general, more relevant studies are needed.